Abstract
The spread in humans is considered one of the most studied issues among other illicit products. Nevertheless, cannabis/cannabinoids' safety remains unsolved and controversial. Cannabidiol, a component of recreational cannabis, is now found in a multitude of legal or illegal medicinal cannabis preparations, dietary supplements, foods, cosmetics, etc., in uncontrollable combinations with the psychoactive tetrahydrocannabinol (THC). Despite the conflicting findings of many research groups regarding the safe administration of cannabinoids in general, in all age/race groups, these limitations have not been particularly emphasized. Fortunately, the significant increase in its consumption in the elderly has led reliable international organizations to strongly question the long-term cannabidiol toxicological "immunity", highlighting these risks by classifying it as a particularly CMR substance (ANSES). Serious elderly problems have also been recently recorded, especially at dosages greater than 2mg/day of Cannabidiol (EFSA). In this short article, some of the Cannabidiol receptors, their potential therapeutic applications, side effects, and their interactions with prescription drugs/comorbidities are listed.
In conclusion, Cannabidiol must immediately be addressed by law, as a multi-potent and not harmless drug, with the aim of an effective measure against the public and individual health "invisible siege", on a global scale, otherwise its negative cost outweighs any healing benefit.
