Current Issue (Volume - 2 | Issue - 4) at IgMin Research

Six alkaloid compounds were isolated (the discovery of a natural drug, which is a combination of the six alkaloid compounds). Alkaloids viz., 1,3,5-Triazine-2-carboxylic acid, 4-amino-6-methyl; 1,2,4-Triazino[5,6-E][1,2,4]-triazine-3,6-dione, hexahydro; 2-(4,5-Dihydro-3-methyl-5-oxo-1-phenyl-4-pyrazole)-5-nitrobenzoic ...acid; 4-metyl-3,4-dihydro-[1,2,3] trizolo [4,5-d] pyrimidine-5,7-dione; Propanoic acid-3-(perhydro-2,5-dioxo-imidazol [4,5-d] imidazole-1-yl) and 1,2,3-Triazolo[4,5-f] benzotriazole- 4,8(4H,8H)-dione, were isolated from Cinnamomum verum cortexes by using ethanolic acetic acid, sulphuric acid, and ammonia solvents, and they were characterized by using preliminary qualitative tests, gas chromatography-mass spectrumGC-MASS.The medicinal efficacy was studied for these six alkaloidic compounds theoretically by using the Autodock program and the results showed the presence of high efficacy of the compounds. Then the medicinal efficacy was measured biologically for the six compounds mixture in vitro depending on the synergistic interaction principle by using various concentrations (5, 10, 15, 20, and 25 mg/ml) by using of agar diffusion technique. The results showed that the six alkaloidic compounds’ mixture is biologically active against Alternaria alternate fungus, where the inhibition zone diameters were recorded equal to 27, 33, 41, 45, and 49 mm respectively towards the pathogenic fungus. Also, cytotoxicity tests for the different concentrations of six active alkaloid compounds mixture proved there is no toxic effect belonging to them towards red blood cells, and no hemolysis effect appeared in blood cells. Therefore, six alkaloid compounds isolated from Cinnamomum verum cortexes can be used as active drugs for the treatment of various diseases especially those caused by pathogenic fungi represented by Alternaria alternate, without any side effects.Read more

Uremic toxins (UTs) are compounds derived from the metabolism of dietary molecules such as tryptophan (Indossyl Sulphate, IS) and phenil-alanine (P-Cresyl Sulphate, PCS), that are normally eliminated by the kidneys of healthy patients. The accumulation of such toxins is an indicator of kidney disease at different degre...es of severity, and the toxins can be found as free or protein bound in human biological samples. The toxicity of such compounds causes the loss of several biological functions, and the subjects suffering from such complications will need, more often than not, hemodialysis to properly excrete these toxins. Despite this not being a resolutive, but rather a symptom managing clinical approach, this is the most common course of treatment. Two analytical methods are proposed to quantify both the protein-bound and free forms of IS and PCS (HPLC-UV for the former; LC-MS/MS with ESI negative ionization for the latter), with lower variability and higher robustness than what is currently proposed, allowing for a precise simultaneous determination of the aforementioned UTs.Read more

This study presents a new assessment tool, FIKR (Facet, Insight, Knowledge, and Resilience) Personality Traits (PTs) for organisational talent development and leadership. The FIKR assessment tool offers a thorough framework for developing talent and leadership, covering facets, insights, knowledge, and resilience. By u...sing these elements, individuals can enhance their ability to successfully and strategically guide and influence others. Gaining self-awareness of one’s strengths and shortcomings, harmonising personal values with objectives for developing talents, obtaining the requisite information and abilities, and cultivating resilience not only promotes personal progress but also cultivates the potential of people within the organisation. By embracing the interaction of these FIKR characteristics, one may adopt a comprehensive and influential approach to talent development and leadership.Read more

The present study is based on the examination of specimens housed in different museums and collections, including those of Lianghong Bin (China), Bernd Jaeger (Germany), Saeed Azadbakhsh (Iran), Alexander Anichtchenko (Latvia), Martin Hackel (Czech Republic), Ron Felix (Germany), and the first author (ZACP). A prelimin...ary survey was randomly conducted in various areas of Pakistan from 2016 to 2023. A precise investigation revealed 17 subspecies and 36 species within 31 genera, distributed across 12 subfamilies in the family Carabidae. This survey also documented twenty-three new records for the country, expanding our understanding of their distribution. All determinations presented here are confirmed and validated by Löbl & Löbl (2017). Subfamily Harpalinae tribe Anthiini with 02 species Anthia (Anthia) sexguttata mannerheimii, A. (A.) sexguttata sexguttata Brachininae with 03 species Brachinus (Aploa) nobilis Pheropsophus (Stenaptinus) catoirei, P. (S.) lissoderus, P. stenoderus. Subfamily Broscinae with 01 species Broscus punctatus. Subfamily Carabinae with 07 species Carabus (Imaibius) caschmirensis fortetuberculatus, C. (I.) wittmerorum, Calosoma (Caminara) imbricatum andrewesi, C. (C.) maderae indicum, C. (C.) imbricatum imbricatum, C. Calosoma (Compalita) Olivieri, C. (Calosoma) scabrosum roeschkei. Subfamily Dryptinae, Dryptini with 01 species Drypta (Drypta) lineola virgata, tribe Galeritini with 04 species records Planetes bimaculatus, Zuphium (Zuphium) olens olens, Galerita indica, Ophionea (Ophionea) indica. Subfamily Harpalinae with 03 species Idiomelas fulvipes indus, Metacolopodes buchanani, Microlestes discoidalis, tribe Chlaeniini with 12 species Chlaenius (Amblygenius) atripes, C. (A.) bengalensis, C. (A.) cookie, C. (A.) Chlaenius (Amblygenius) quadricolor orientalis, C. (Pachydinodes) hamifer, C. (P.) pictus, C. (P.) posticus, C. pretiosus, C. (Chlaenites) spoliatus spoliatus, Harpaglossus opacus, H. (Cryptophonus) tenebrosus, H. (Pseudophanus) meridianus, tribe Cyclosomini with 03 species records, Masoreus (Masoreus) orientalis orientalis, Caphora afghani, Tetragonoderus (Tetragonoderus) lindemannae, tribe Licinini with 06 species record, Diplochiela (Diplocheila) laevigata, Glycia spencei, Eucolliuris fuscipennis, Platytarus faminii faminii, Syntomus lateralis lateralis,     Trichis maculata. Subfamily Melaeninae with 03 spies, Cymbionotum (Cymbionotum) striatum, C. Cymbionotum candidum, C. semelederi, tribe Panagaeini with 03 species Microschemus flavopilosus, M. arabicus, Craspedophorus elegans. Subfamily Harpalinae with 01 species Sphodrus leucopthalmus. Subfamily Scaritinae, Scaritini with 02 species Scarites (Scallophorites) guineensis, S. (Scarites) procerus eurytus, subfamily Siagoninae with 01 species Siagona dilutipes and subfamily Trechinae, Bembidiini with 01 species Bembidion (Notaphocampa) niloticum niloticum.Read more

There is constructed a qualitative model of the electrical conductivity of semiconductors irradiated with sufficiently high-energy particles. At certain conditions (irradiation temperature and dose, and subsequent thermal treatment), high-energy particles fluence, in addition to primary and secondary point radiation de...fects, forms a number of nano-sized disordered regions, highly conductive (“metallic”) compared to the semiconductor matrix. Their high total volume fraction can lead to the charge major carriers’ effective Hall mobility significantly exceeding that of the matrix. Due to elastic stresses created by these disordered inclusions, a high concentration of point radiation defects tends to form defective shells. In certain temperature ranges, such nanosized core-shell structures act as capacitors storing the electric charge sufficient for the Coulomb blockade of the major current carriers. Transformation of high-conductive inclusions into low-conductive (“dielectric”) ones manifests in a noticeable decrease in effective Hall mobility. The proposed model qualitatively explains all the experimental data available on single-crystalline n- and p-type silicon irradiated with high-energy electrons and protons and isochronously annealed.Read more

We present here the incompleteness of the Copenhagen interpretation regarding the impossibility of explaining the transition from the exact quantum mechanics to the Born-Oppenheimer approximation, where the inaccurate method captures phenomena like spontaneous symmetry breaking, but this is impossible to achieve with e...xact equations. The solution to this dilemma lies in the revision of quantum field theory which bounds together internal and external (vibrational, translational, and rotational) degrees of freedom in a similar way as the Lorentz transformation deals with space and time. This is the only way how to exactly mathematically justify the corrections beyond the Born-Oppenheimer approximation (Born-Huang ansatz). The consequences are overwhelming: It reveals the wrong BCS theory of superconductivity, derived on the basis of the incomplete quantum field, and all erroneous theories inspired by the BCS one (e.g. Higgs mechanism). Moreover, the second Bohr complementarity emerges from the mechanical wholeness and field fragmentation, opening the door for the megascopic mirror of the microscopic Copenhagen interpretation and for the explanation of megascopic quantum phenomena. Finally, we get an entirely new look at the meaning of physics and chemistry: The first one deals with microscopic and the second one with megascopic phenomena.Read more

This work is carried out to fill the epistemic and hermeneutical gap within Igbo socio-metaphysical space. Notable works have been done in Igbo studies, however, the place of the Dibia in Igbo ontology has been neglected, hence the current work. The researchers combined library and fieldwork approaches in executing thi...s work. In the end, the research notes that modern Igbo people have neglected the place and activities of the Dibia. Noting that the Dibia being the active presence of the God[s] among the people is an indispensable persona in the Igbo existence. Therefore, the current crisis of relevance the people are experiencing is a result of this neglect. The works, therefore, conclude that if the Dibia and her activities are brought back to the centre stage of Igbo existence, the socio-political and economic crises of the moment would have been a history.Read more

Energy Valley Optimizer (EVO) is one of the recent metaheuristic algorithms. It draws inspiration from advanced principles in physics related to particle stability and decay modes. This paper presents a new Energy Valley Optimizer (EVO) and levy flights that are hybrid to improve the EVO in solving optimization problem...s. Levy flight is one of the most important randomization techniques. Fifteen mathematical test functions (five unimodal functions, four multimodal functions, and six composite functions) are solved with the proposed algorithm. We also compare our results with previous results of metaheuristic algorithms. The statistical results show that the results of the Levy Energy Valley Optimizer (LEVO) outperform other algorithms in almost all mathematical test functions.Read more

Cyber Threat Analysis (CTA) in current conflicts focuses on identifying, monitoring, and assessing potential cyber threats. The main objective is to understand how the parties to the conflict use information and network technologies to conduct warfare, espionage, disinformation, or attacks on digital infrastructure. Th...is analysis includes the identification of actors involved in conflicts and their targets in cyberspace, as well as the analysis of techniques and tools used in cyber activities. The aim of the article is to identify the role of cyber threat analysis in the context of two current conflicts - the war in Ukraine and the Hamas attack on Israel. The article describes the essence of cyber threat analysis. The research problem focuses on identifying and understanding the role of cyber threat analysis in these conflicts and their potential consequences for international security and regional stability. Through the analysis of reports, online sources, and scientific literature, the article aims to familiarize readers with the role of cyber threat analysis in the context of these conflicts and to propose possible strategies for cyber risk management in the face of contemporary armed conflicts. The results of the analysis of cyber threats (CTA) in current conflicts include the identification of specific actors operating in cyberspace, their modus operandi, their objectives, and the techniques and tools used. In addition, the analysis can reveal existing vulnerabilities in digital security and areas that are particularly vulnerable to attacks. To sum up, it is necessary to create recommendations and directions for changes regarding the strengthening of digital security measures, such as software updates, implementation of network security, and increasing staff awareness of cyber threats. In addition, the CTA may suggest the need for better international cooperation to combat cyber threats and the need to develop strategies to prevent and respond to cyber-attacks.Read more

The “System for Detecting Moving Objects Using 3D LiDAR Technology” introduces a groundbreaking method for precisely identifying and tracking dynamic entities within a given environment. By harnessing the capabilities of advanced 3D LiDAR (Light Detection and Ranging) technology, the system constructs intri...cate three-dimensional maps of the surroundings using laser beams. Through continuous analysis of the evolving data, the system adeptly discerns and monitors the movement of objects within its designated area. What sets this system apart is its innovative integration of a multi-sensor approach, combining LiDAR data with inputs from various other sensor modalities. This fusion of data not only enhances accuracy but also significantly boosts the system’s adaptability, ensuring robust performance even in challenging environmental conditions characterized by low visibility or erratic movement patterns. This pioneering approach fundamentally improves the precision and reliability of moving object detection, thereby offering a valuable solution for a diverse array of applications, including autonomous vehicles, surveillance, and robotics.Read more

This case study investigates the implementation of Virtual Reality (VR) technology in facilities management Competency-Based Training (CBT) within one of Singapore’s leading facilities and township management companies. Traditionally, workplace training in facility management has relied heavily on lecture-based m...ethods, often resulting in insufficient preparation and a high turnover rate among newly onboarded staff. To address this challenge, this study explores the conversion of training materials into VR-based courseware, enabling immersive and interactive learning experiences.Two groups of newly onboarded staff underwent either traditional lecture-based or VR training sessions. Results indicate that those trained using VR exhibited a better comprehension of the material and higher levels of motivation compared to their counterparts in the traditional lecture-based group. However, it was noted that VR training carries the risk of cybersickness, with some participants reporting symptoms such as dizziness. To mitigate this issue, insights from existing literature on cybersickness are incorporated to enhance future VR training materials.This paper studies the application of VR in Facilities Management Competency-based training within the discourse of Industrie 5.0, the latest evolution of industrial technology that emphasizes human-machine collaboration and smart technologies such as VR. By leveraging VR technology for training purposes, this initiative aligns with the principles of Industrie 5.0, fostering innovation and efficiency in facility management practices. Overall, this research underscores the potential of VR in revolutionizing training methodologies within the practices of facilities management while addressing associated challenges to ensure optimal learning outcomes.Read more

The article presents a case study on the Investigation of lateral vibrations in the turbine-generator unit 5 of the Inga 2 hydroelectric power plant in the Democratic Republic of the Congo. Lateral vibrations were experimentally determined using twelve proximity and eddy-current probes, positioned on each measurement p...lane. The results were analyzed using the Dasylab and R software. Hence, it was observed that the vibration amplitudes of the upper guide bearing, lower guide bearing, and pivot/rotor exceeded acceptable or critical limit values of the international vibration standard for a rotating speed between 100-250 rpm. These excesses can lead to rotor mass imbalances, the eccentricity of the rotor axis relative to the rotation axis of the shaft, and the deformation of the coupling shaft between the upper rotor shaft and the turbine rotor shaft. Subsequently, the means and the variances of the vibration amplitudes were evaluated and compared to the reference values of the international standard. The results of the compliance analysis revealed statistically significant differences between the measured amplitudes and the reference values. Thus, it indicates deviations from international specifications.Read more

The article discusses the methods for determining the maturity of grain and describes its behavior during harvesting, to optimize the selection of the grain moisture state, discusses the requirements for the choice of measurement method and the design of moisture control measuring devices, as well as its high accuracy ...and the possibility of measuring from field conditions, collection, storage, transportation, and industrial processing and release of finished products of granular materials.The purpose of the study is to improve the efficiency of control and management of complex technological processes and moisture control devices for granular bulk materials of plant origin through the development of systems for automatic and automated control of the electrophysical characteristics of grain products and to increase the reliability of quantitative and qualitative assessments of production and technological measurement information. To achieve this goal, it is necessary to conduct analytical and experimental studies of the possibility of creating an express method for controlling the moisture content of grain and products of their industrial processing and the development of a moisture meter for automated control of raw material parameters during acceptance and storage at grain processing enterprises. The article discusses the scientific and methodological foundations for measuring the electrophysical characteristics of grain products of agricultural production and the implementation on this basis of the functional subsystem of information support by the Automated Process Control System for Controlling the Mass Ratio of Moisture of Plant Origin Materials. A critical analysis of the current state of the theory and practice of automatic control of electrophysical characteristics of grain products and the identification of the trend of their further development and improvement are carried out. A mathematical model of the interaction of a high-frequency field with a granular material has been constructed, where the influence of the elastic properties of the grain on the electrical characteristics of the electromagnetic wave, which distinguishes its behavior in the field of a high-frequency wave from many other dielectrics, has been substantiated, and the influence of a large number of various disturbing factors has been studied, often the measurement results cannot be applied in the control of the technological process due to the uneliminated error, which is the cause of inaccurate information. Primary measuring transducers of electrophysical parameters of grain products are proposed, and their mathematical models are considered. A functional scheme of the measuring device based on the dielcometric method of moisture control of grain and granular materials has been developed, and metrological characteristics have been given.Read more

Reconstruction of pulverized coal boilers BKZ (Barnaul Boiler Plant, steam productivity 160 t/h, pressure 100 kgf/cm2, fuel: natural gas/fuel oil) with steam productivity of 160 t/h, converted to gas combustion, and an increased load capacity to 210 t/h, has been carried out. As part of the boiler modernization, a chem...ical water treatment system was reconstructed, significantly improving the quality of feedwater: hardness not exceeding 0.3-0.5 µeq/kg; SiO2 not exceeding 18 µg/kg, and electrical conductivity Х=0.6-1.0 µS/cm. The previously used phosphate regime for boiler water was replaced with a chelant-based regimen using trilon B. During operation, widespread damage to the screen tubes occurred. Circulation tests were conducted on one of the boilers, and an analysis of internal deposits was performed.It was determined that water circulation in the side screen is stable, and its velocities correspond to calculated values. The main cause of metal ruptures in the screen tube is metal corrosion, as well as local overheating of the wall caused by the formation of a steam layer due to the detachment of internal deposits.Read more

Sri Lanka is facing an energy crisis due to insufficient exploitation of renewable energy resources and high reliance on imported fossil fuels. Building-integrated PV (BIPV) systems are one approach that provides various benefits in countries with limited land areas and congested metropolitan regions for ensuring energ...y security. This study was conducted to evaluate the rooftop solar PV capacity and yearly electricity generation potential in selected provinces in Sri Lanka. The study found 115 km2 of rooftop area for solar PV installation in four Sri Lankan provinces; Sabaragamuwa, Western, Northern, and North Central with approximately 25 GW of solar PV installation capacity could lead to annual electricity generation of 45 TWh which could reduce carbon emissions by 20 million tCO2 per year.Read more

Fungi, and especially mold fungi, play a very important role in natural environments, as well as in the food industry for the production of many specialized products. However, many of them, under favorable conditions, are capable of producing toxic compounds called mycotoxins. Many of them have an adverse effect on the... growth and development of all groups of organisms, including humans. Mycotoxins can appear in all food products and animal feed. Mycotoxins accumulated in food of plant and animal origin and consumed by humans can accumulate in various tissues and organs, which results in disorders in their functioning and may cause cancer. Plants have the ability to defend themselves against mycotoxins by neutralizing them as a result of the glycosidation process. Mycotoxins neutralized in this way are called “masked mycotoxins”, which are not toxic to plants, but after entering the body of animals or humans in the digestive tract, they return back to their original toxic form. Let’s appeal and spread knowledge about mycotoxins because they pose a constant threat to the health of people and farm animals.Read more