Wanderson Gabriel Gomes de Melo, MSc

Wanderson Gabriel Gomes de Melo, MSc, is a PhD student in Health Biotechnology at the Federal University of Piauí (UFPI), Brazil, and Co-Guest Editor of the Special Issue on Translational Bioengineering for Regenerative Applications in Biotechnology & Bioengineering. His research bridges computational and experimental approaches to tissue repair, regenerative biology, and biomaterial-guided cellular modulation. With expertise in RNA-seq integration, gene regulatory network modeling, and stem cell–microenvironment interactions, he advances innovative strategies for renal pathophysiology and tissue engineering. His work has been published in leading journals such as Canadian Journal of Physiology and Pharmacology and ACS Omega. Recognized with awards including the Best Poster in Cardiovascular and Renal Pharmacology (2024) and participation in Kyushu University’s K2-SPRING program (2025), he continues to contribute to the global dialogue on regenerative bioengineering.

Rede Nordeste de Biotecnologia (Renorbio), Universidade Federal do Piauí (UFPI), Brazil Email: [email protected] | ORCID: 0000-0002-5120-2281

Research Interests Tissue repair and regenerative biology; stem cell–microenvironment interactions; biomaterial-guided cellular modulation; mitochondrial control of cell fate; transcriptomic integration and gene regulatory network modeling in renal pathophysiology.

Education

• PhD in Health Biotechnology (2025–present): Renorbio, UFPI (CAPES Fellow).
• MSc in Cellular Biotechnology and Applications (2025): UFPI (CAPES Fellow).
• BSc in Veterinary Medicine (2021): UFPI.

Research Experience

• Computational: Bulk RNA-seq integration (DESeq2, limma); pathway enrichment; protein–protein interaction networks; ortholog mapping; gene regulatory network reconstruction; machine learning for regulators; R/Python pipelines for network pharmacology and cross-dataset analysis in tissue repair/remodeling.
• Experimental: In vitro mesenchymal stem cell culture; biomaterial–cell interactions; bioactive hydrogel and composite scaffold development/characterization for tissue engineering.

Selected Publications (Full list via ORCID)

• Melo WGG et al. GLP-1 and diabetic nephropathy share key molecular targets. Can J Physiol Pharmacol (2026).
• Melo WGG et al. Behavioral dynamics of medicinal signaling cells from porcine bone marrow. Can J Physiol Pharmacol (2024).
• Da Silva MH et al. Heterojunction of titanate nanotubes enhanced by curcumin. Colloids Surf A (2025).
• Vieira de Sousa TW et al. In situ preparation of composite scaffolds for bone tissue engineering. ACS Omega (2025).
• Reis FS et al. Development of scaffold based on buriti oil and PEG-400. ACS Omega (2025).
• De Oliveira Bezerra D et al. Kidney/aorta ratio for renal morphometric determination in swine. Comp Med (2024).

Awards

• Best Poster Award, Cardiovascular and Renal Pharmacology, Brazilian Society of Pharmacology (2024).
• K2-SPRING International Research Program, Kyushu University, Japan (2025).

Technical Skills

• Bioinformatics: RNA-seq analysis; pathway enrichment; gene networks; machine learning in transcriptomics; R/Python.
• In Silico: Network pharmacology; molecular docking; DFT modeling.
• Experimental: Stem cell culture; biomaterial synthesis/characterization; histological/molecular tissue analysis.