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Drug Metabolism is a critical field of study that explores the biochemical processes by which the body transforms pharmaceutical compounds. This discipline investigates the enzymatic pathways involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs. Understanding drug metabolism is fundamental to drug development, as it determines the efficacy, safety, and potential side effects of therapeutic agents. By studying the enzymes responsible for drug biotransformation, researchers can predict how drugs interact within the body, identify genetic variations that influence metabolism, and optimize dosing regimens.
The study of drug metabolism also has profound implications for personalized medicine, as individual genetic differences can affect how drugs are processed and how they impact different patients. Furthermore, drug metabolism research informs the design of new drugs, helping scientists to overcome issues of drug toxicity, drug resistance, and interactions with other medications. It is a dynamic and interdisciplinary field at the intersection of pharmacology, biochemistry, and toxicology, playing a pivotal role in advancing therapeutic strategies and improving public health outcomes.
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Research Articles
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