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Our aim is to support a culture of interdisciplinary research for the swift advancement of knowledge.

Engineering Group (1)

Research Article Article ID: igmin157
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Open Access Policy refers to a set of principles and guidelines aimed at providing unrestricted access to scholarly research and literature. It promotes the free availability and unrestricted use of research outputs, enabling researchers, students, and the general public to access, read, download, and distribute scholarly articles without financial or legal barriers. In this response, I will provide you with an overview of the history and latest resolutions related to Open Access Policy.

Modeling of an Electric-fired Brick Oven, Directly Heated
by André-Jacques Nlandu Mvuezolo, Jean Noël Luzolo Ngimbi and Lucien Mbozi

The purpose of this article is to propose a model of an electric-fired brick oven, with the aim of eliminating the imperfections presented by traditional brick ovens. To complete this study, we used the concepts of heat transfer, and material resistance, as well as those of computer-aided mechanical design.Deemed satisfactory, the results found give a yield of 94.5% and a cooking time of 7.29 hours based on 2000 bricks cooked.

Energy Systems

Medicine Group (4)

Research Article Article ID: igmin158
Cite

Open Access Policy refers to a set of principles and guidelines aimed at providing unrestricted access to scholarly research and literature. It promotes the free availability and unrestricted use of research outputs, enabling researchers, students, and the general public to access, read, download, and distribute scholarly articles without financial or legal barriers. In this response, I will provide you with an overview of the history and latest resolutions related to Open Access Policy.

Balancing Act: Exploring the Interplay Between Human Judgment and Artificial Intelligence in Problem-solving, Creativity, and Decision-making
by Abdulrahman M Al-Zahrani

This study explores the repercussions of excessive reliance on Artificial Intelligence (AI) on human cognitive processes, specifically targeting problem-solving, creativity, and decision-making. Employing qualitative semi-structured interviews and Interpretative Phenomenological Analysis (IPA), it delves into the nuanced challenges and risks stemming from an overemphasis on AI. The research illuminates a nuanced landscape: while AI streamlines problem-solving tasks and provides valuable support, there’s a crucial need to safeguard human j...udgment and intuition. In the realm of creativity, divergent viewpoints emerge, underscoring concerns regarding AI’s potential limitations and advocating for a harmonious interplay between AI-generated suggestions and individual creative thought. Regarding decision-making, participants recognize AI’s utility but underscore the necessity of blending AI insights with critical thinking and consideration of unique circumstances. They caution against complacency, advocating for a judicious equilibrium between AI guidance and individual expertise. This study innovates by providing multifaceted insights into the complexities of AI-human interaction, uncovering nuanced perspectives on its impacts across problem-solving, creativity, and decision-making domains. By bridging this gap, it advances understanding of how AI integration influences cognitive processes, offering practical implications for fostering a balanced approach. Its innovative methodology combines qualitative interviews and IPA, offering rich, nuanced data that provide a deeper understanding of the subject matter. This research serves as a beacon for promoting awareness of the risks associated with overreliance on AI, advocating for a mindful integration that upholds human agency while leveraging AI capabilities effectively.

Psychiatry
Brief Communication Article ID: igmin159
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Open Access Policy refers to a set of principles and guidelines aimed at providing unrestricted access to scholarly research and literature. It promotes the free availability and unrestricted use of research outputs, enabling researchers, students, and the general public to access, read, download, and distribute scholarly articles without financial or legal barriers. In this response, I will provide you with an overview of the history and latest resolutions related to Open Access Policy.

Fibrin Contributes to an Improvement of an in vitro Wound Repair Model using Fibroblast-populated Collagen Lattices
by Mario Chopin-Doroteo, Aldo Montes de Oca-Delgado, Rosa M Salgado and Edgar Krötzsch

Incisional acute wounds of the skin are characterized by a rapid biomechanical response by stromal cell contraction that joins the wound lips through the fibrin cloth. In this work, we have performed an in vitro model using Fibroblast-Populated Collagen Lattices (FPCLs) that partially mimic that physiological process. Injured FPCLs under relaxed or stressed conditions were evaluated over time, and cross-sections of the lattices were stained with picrosirius red. Wounds filled with fibrin in relaxed FPCLs were closed earlier than controls, the f...ibrillar pattern of the collagen lattice was different between the wound and the edges of the lattice. On the other hand, stressed FPCLs did not close wounds, even those filled with fibrin, because the tension generated from the lattice borders maintained high tension towards the wound. Controls or fibrin-treated stressed FPCLs, showed high tension in the wound matrix, characterized by the high packing of collagen observed like yellow-red birefringent fibers when stained by picrosirius red. Despite wounds that remain open, fibrin-treated FPCLs exhibited less wound area than controls. With this work, we have demonstrated that FPCL models can be used to study wound closure, mainly when they are improved with other elements of the wound environment that allow us to analyze the biological process.

Dermatology Pathology
Review Article Article ID: igmin160
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Open Access Policy refers to a set of principles and guidelines aimed at providing unrestricted access to scholarly research and literature. It promotes the free availability and unrestricted use of research outputs, enabling researchers, students, and the general public to access, read, download, and distribute scholarly articles without financial or legal barriers. In this response, I will provide you with an overview of the history and latest resolutions related to Open Access Policy.

Breast Cancer: The Road to a Personalized Prevention
by Zaira Grattagliano and Asia Grattagliano

Breast cancer is the most common type of cancer in women worldwide. It can be spread when cancer cells get into the blood or lymph system and then are carried to other parts of the body. As it is one of the leading causes of death among women, this study aims to identify the most relevant risk factors for breast cancer through several prevention methods for early detection. The social impact of breast cancer is so strong that the World Health Organization (WHO) has established 19 October as International Breast Cancer Day. The pink ribbon is th...e symbol of this important day worldwide. The objective is precisely to raise awareness among the population about the disease and promote access to timely and effective diagnoses, checks, and treatments.Good prevention should be carried out through behavior or lifestyle modifications (e.g., diet, physical activity, alcohol limitation, etc.). Although, certain risk factors cannot be modified (e.g., aging, family history). Screenings are a fundamental tool to deal with breast cancer, even if sometimes they are not enough as in the case of interval cancers or in cases of particularly ambiguous presentation. Worldwide organizations recommend screening by means of ultrasound, mammography, and magnetic resonance, with appropriate follow-up for an abnormal screening test. To avoid overdiagnosis and overtreatment that can lead to long-term complications and false negatives, these screening differs by recommended ages and frequency. Identification of women at risk for BRCA1 and BRCA2 mutations is also recommended with a referral for genetic testing and, in the presence of dubious lesions, a biopsy is needed. In order to fight this disease, is important to act on time, so, information is fundamental. First of all, the female population should be conscious of risk factors and of the importance of breast examinations from a young age, lastly, they should be aware of the possibility of joining programs of free screening.

Clinical Medicine Obstetrics & GynecologyGenetics
Review Article Article ID: igmin161
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Open Access Policy refers to a set of principles and guidelines aimed at providing unrestricted access to scholarly research and literature. It promotes the free availability and unrestricted use of research outputs, enabling researchers, students, and the general public to access, read, download, and distribute scholarly articles without financial or legal barriers. In this response, I will provide you with an overview of the history and latest resolutions related to Open Access Policy.

Preventing Rectal Toxicity in Prostate Cancer: Diet and Supplement Alternative to Enemas or Rectal Spacer
by Fabrizio Piro, Daria Cosentino, Ugo Piro, Gabriella Tocci and Luigi Marafioti

Background: Rectal toxicity is an important side effect of prostate cancer irradiation affecting 25% of patients. The role of dosimetric variables has a set of dose-volume constraints and curves to estimate the risk of rectal damage. The rectum position at the time of CT planning is different from the position during radiotherapy. Three methods are available to achieve optimal rectum position: enema; prostate cancer spacer; fiber-/fat-free diet. Methods: A 70.2 Gray radiation divided into 26 hypo-fractions was administered to 115 patients ...with prostate cancer by VMAT referred to a single center in Italy. To empty the rectum, all patients were administered a fiber-/fat-free diet and those with Eating Disorders (ED) were also added with activated charcoal (2 tablets/day) and a macrogol-based medical device (2 sachets/day). During treatment, the volumetric amount of rectum in the target was measured by comparing control-CT with simulation-CT, and acute toxicity was also checked. Results: The rectum position during control-CT in diet-only patients (29) predicted toxicity recorded during treatment, while in the ED group rectum position was adherent to position during simulations. Rectal volume target > 0.25 cc receiving a dose > V70 caused acute G3 toxicity that attenuated or worsened with rectal displacement. Acute rectal toxicity occurred in 6/29 (20.68%) patients (1 G3, 5 G1) in the diet-only group, while only in 1/86 (1.16%) patients (G1) in the ED group. No chronic toxicity was recorded in either group. Conclusion: Prostate cancer patients treated with VMAT, diet, charcoal, and macrogol emptied the rectum optimally and reduced incidence and severity of acute rectal toxicity, also with benefit on late toxicity.

Radiation Therapy
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