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Abstract

Meng Zhang Editor at IgMin Research

Our mission is to foster interdisciplinary dialogue and accelerate the advancement of knowledge across a wide spectrum of scientific domains.

Biography

2020.11-now, Principal Investigator, the First Affiliated Hospital, School of Medicine, Zhejiang University
2020.03-2020.09, Research fellow, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
2015.09 – 2020.01, Ph.D., Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
2016.01-2016.06, Cooperation in Dr. Jacob Hanna’s lab (Weizmann institute of science, Israel)
2012.09 – 2015.06, M.S., An’hui University, Hefei, China
2008.09 – 2012.06, Bachelor Degree of Biotechnology, He’nan Normal University, Xinxiang, China

Reasearch Interest

Erythroid differentiation of pluripotent stem cells (PSCs) is an important research direction to alleviate the clinical "blood shortage" problem, but the erythroid cells from iPSCs are not mature enough to meet the clinical standards. Our team focus on to optimize the differentiation system from PSCs by screening with small molecular library and Crispr/Cas9 library to solve the problem of poor efficiency of enucleation. We also explore the epigenetic and transcriptional mechanism of terminal erythropoiesis.