IGMIN: We're glad you're here. Please click 'create a new query' if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click 'take me to my Query.'
Welcome to IgMin Research – an Open Access journal uniting Biology, Medicine, and Engineering. We’re dedicated to advancing global knowledge and fostering collaboration across scientific fields.
Welcome to IgMin, a leading platform dedicated to enhancing knowledge dissemination and professional growth across multiple fields of science, technology, and the humanities. We believe in the power of open access, collaboration, and innovation. Our goal is to provide individuals and organizations with the tools they need to succeed in the global knowledge economy.
IgMin Publications Inc., Suite 102, West Hartford, CT - 06110, USA
We support interdisciplinary exchanges that promote swift advancements in various scientific disciplines.
Biography
Dr. Yuebin Tan is a distinguished clinical researcher and author based in the United States, currently affiliated with Georgetown University’s Department of Biochemistry and Molecular and Cellular Biology in Washington, D.C. As an active contributor to IgMin Research, a multidisciplinary open-access journal, he has co-authored impactful studies in clinical medicine and rehabilitation.
In January 2025, Dr. Tan co-published “The Role of CCL18 in Rheumatoid Arthritis Diseases” alongside Ningna Han and Xiaofeng Wu. This mini-review probes the role of chemokine CCL18 as a therapeutic target in rheumatoid arthritis, detailing its mechanisms in synovial inflammation and potential for future drug development. Shortly thereafter, in April 2025, he was the corresponding author on “Risk of Nutritional Deficiencies and Changes in Dietary Patterns after Bariatric Surgery.” This clinical study evaluated health and dietary shifts across 113 patients post-surgery, highlighting critical nutritional changes and the necessity of pre-operative assessment and ongoing post‑operative care.
His contributions have garnered recognition within IgMin, including a certificate for the bariatric surgery article issued in April 2025. Dr. Tan’s interdisciplinary collaborations span institutions in China, Hong Kong, and the United States, emphasizing his global scientific reach .
At Georgetown University, he brings expertise at the intersection of molecular biology, clinical biochemistry, and patient-centered outcomes. His work on inflammatory biomarkers and surgical nutrition reflects a deep commitment to translating molecular insights into tangible therapeutic guidance, thereby advancing both academic understanding and real-world patient care.
Research Interest
Dr. Yuebin Tan’s research interests lie at the intersection of clinical biochemistry, molecular biology, and patient-centered translational medicine. He focuses particularly on the molecular mechanisms of inflammation and immune regulation in chronic diseases such as rheumatoid arthritis. His work explores chemokines like CCL18 as potential therapeutic targets, aiming to develop more precise and personalized treatment strategies. In addition to immunological research, Dr. Tan is deeply engaged in studying metabolic health, with a specific focus on the nutritional and physiological impacts of bariatric surgery. He investigates postoperative dietary patterns, nutritional deficiencies, and long-term metabolic outcomes to inform clinical best practices. Dr. Tan’s multidisciplinary approach combines bench-side molecular analysis with clinical data, reflecting his commitment to bridging the gap between research and patient care. His broader goal is to contribute to the development of targeted therapies and interventions that improve quality of life and health outcomes for individuals with chronic or post-surgical conditions.
Open Access Policy refers to a set of principles and guidelines aimed at providing unrestricted access to scholarly research and literature. It promotes the free availability and unrestricted use of research outputs, enabling researchers, students, and the general public to access, read, download, and distribute scholarly articles without financial or legal barriers. In this response, I will provide you with an overview of the history and latest resolutions related to Open Access Policy.
byXiaofeng Wu, Cailin Pan, Ningna Han and Yuebin Tan
Background: Nutrient deficiency and dietary restriction are common after bariatric surgery, regardless of weight loss. We aimed to evaluate the postoperative change in dietary patterns. Methods: 113 patients who underwent bariatric surgery from 2018 to 2021 were followed up at baseline and three months after surgery. Anthropometric and biochemical data were collected retrospectively, and the diet was analyzed by a food frequency questionnaire (FFQ). Results: Postoperative weight, body mass index (BMI), and % body fat decreased signifi...cantly (p < 0.001). Prealbumin (PA) and retinol-binding protein (RBP) levels decreased significantly at 3 months post-surgery (p < 0.001); however, vitamin D (VD) , zinc, and albumin (ALB) levels increased (p < 0.05). Hemoglobin (HGB) in the Roux-en-Y gastric bypass (RYGB) group was lower than that in the sleeve gastrectomy with jejunal bypass (SGJB) and the sleeve gastrectomy (SG) group (p < 0.05). The intake of cereals, tubers, legumes, meat, poultry, and aquatic products decreased (p < 0.001), whereas the intake of vegetables (except for soybeans), fruit, eggs, milk and dairy products, and water increased (p < 0.05). The RYGB group had a higher intake of cereals, tubers, and legumes than that in the other groups (p < 0.05), although there was no association between the reduction of intake in these food groups and weight loss. Conclusion: Bariatric surgery has a beneficial impact on weight loss and dietary patterns. Preoperative nutritional assessment and continuous follow-up are critical with bariatric surgery to prevent weight regain and malnutrition.
Open Access Policy refers to a set of principles and guidelines aimed at providing unrestricted access to scholarly research and literature. It promotes the free availability and unrestricted use of research outputs, enabling researchers, students, and the general public to access, read, download, and distribute scholarly articles without financial or legal barriers. In this response, I will provide you with an overview of the history and latest resolutions related to Open Access Policy.
Rheumatoid Arthritis (RA) is a chronic auto-immune disease that mostly occurs in joint space with remarkably painful swelling. RA detail pathologies remain unclear, but several C-C motif chemokines factors and Interleukin have been identified as associated factors and correlated disease-associate activities (such as CCL2, CCL18, IL-6). Among these factors, increasing evidence indicates CCL18 could be an appropriate drug target, as it is highly correlated with disease-associated activities (DAS28) (elevated level of CCL18 in both patient serum a...nd local synovial fluids). High-concentration CCL18 in synovial fluids has been reported to facilitate pro-inflammation factor production, finally resulting in painful swelling in joint space. In vivo studies showed significant drug efficiency with anti-TNF-a treatment (CCl18 suppression). Most current approved drugs target TNF, IL-6, or other factors, but do not target CCL18 directly or indirectly. From this perspective, CCL18 has been believed to be a new target for RA therapeutic drug development.
0000-0003-3936-0460 
